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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
22.73
Human Site:
S216
Identified Species:
35.71
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S216
C
P
L
Y
H
N
L
S
A
D
E
C
K
V
R
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S411
C
P
L
Y
H
N
L
S
A
D
E
C
K
V
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
E177
S
R
D
K
Q
I
E
E
R
M
L
S
H
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S218
C
P
L
Y
H
N
L
S
A
D
E
C
K
V
R
Rat
Rattus norvegicus
Q810T5
612
70496
S217
C
P
L
Y
H
N
L
S
A
D
E
C
K
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S216
C
P
L
Y
H
N
L
S
A
D
E
C
K
V
R
Frog
Xenopus laevis
NP_001079995
617
71123
S216
C
P
L
Y
H
N
L
S
A
D
E
C
K
N
C
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
Q190
K
A
I
E
R
E
K
Q
D
E
E
R
S
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
G163
S
G
G
E
L
V
N
G
N
N
L
A
A
A
L
Honey Bee
Apis mellifera
XP_392324
916
101344
P508
P
L
Y
H
N
T
T
P
Q
A
C
A
E
F
Y
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
Q80
R
R
L
D
E
W
V
Q
S
D
R
L
N
L
A
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
Q126
G
G
P
K
K
K
I
Q
K
K
S
T
G
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
M67
L
E
V
G
T
R
V
M
C
R
W
R
D
G
K
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
I67
N
K
R
L
D
E
W
I
T
T
D
R
I
N
L
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
S128
K
R
E
Q
S
V
A
S
D
G
Q
T
P
H
P
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
100
86.6
6.6
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
N.A.
100
86.6
20
N.A.
6.6
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
40
7
0
14
7
7
7
% A
% Cys:
40
0
0
0
0
0
0
0
7
0
7
40
0
0
7
% C
% Asp:
0
0
7
7
7
0
0
0
14
47
7
0
7
0
0
% D
% Glu:
0
7
7
14
7
14
7
7
0
7
47
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
7
14
7
7
0
0
0
7
0
7
0
0
7
7
14
% G
% His:
0
0
0
7
40
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
7
0
0
7
7
7
0
0
0
0
7
0
0
% I
% Lys:
14
7
0
14
7
7
7
0
7
7
0
0
40
7
7
% K
% Leu:
7
7
47
7
7
0
40
0
0
0
14
7
0
7
14
% L
% Met:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
40
7
0
7
7
0
0
7
14
0
% N
% Pro:
7
40
7
0
0
0
0
7
0
0
0
0
7
0
7
% P
% Gln:
0
0
0
7
7
0
0
20
7
0
7
0
0
7
7
% Q
% Arg:
7
20
7
0
7
7
0
0
7
7
7
20
0
7
34
% R
% Ser:
14
0
0
0
7
0
0
47
7
0
7
7
7
0
0
% S
% Thr:
0
0
0
0
7
7
7
0
7
7
0
14
0
0
0
% T
% Val:
0
0
7
0
0
14
14
0
0
0
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
40
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _